Solid Tumour Section

Disease Myoepithelioma tumours of soft tissue cover a wide range of tumours of various behaviour. While most are of intermediate aggressivity, some metastasize. There is no sex ratio predominance. Mean age at diagnosis is 38 years; with a range of 3-83 years. Of a hundred of cases reviewed by Hornick and Fletcher (2003), 60% were benign and classified as myoepitheliomas or mixed tumors, and 40% were classified as myoepithelial carcinomas or malignant mixed tumours. Amongst cases with benign or low-grade cytology, with a mean follow-up of 3 years, 20% recurred locally and none metastasized. Amongst cytologically malignant cases, with a mean follow-up of 4 years, 40% recurred locally, 1/3 metastasized, and 4 out of 31 patients died. Tumours are positive for epithelial markers, and for S100 or GFAP, or myogenic markers (Gleason and Fletcher, 2007).